New 2-pyrone-based hydrazones: Synthesis, spectral characterisation, UV–visible study and evaluation of the antiradicalar activity

Abstract

The synthesis of new 2-pyrone-based hydrazones has been prepared by the coupling of 6-methyl-2H-furo[3,2-c]pyran-3,4-dione with diazonium salts, obtained by diazotization of aniline derivatives. The structure of all compounds was established by spectroscopic methods, and the structure of the more stable conformer was theoretically confirmed by the potential energy profile analysis. The prepared 2-pyrone-based hydrazone dyes were acetylated and both groups of compounds showed moderate to good radical scavenging activity.